c-myc inhibitor — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T3048	10058-F4	c-Myc Inhibitor	c-Myc , Autophagy
	10058-F4 (c-Myc Inhibitor) is a cell-permeable thiazolidinone that specifically inhibits the c-Myc-Max interaction and prevents transactivation of c-Myc target gene expression; induces cell-cycle arrest and apoptosis.		c-Myc , Autophagy
TN1892	Lusianthridin		Others , c-Myc
	Lusianthridin is a natural product from Dendrobium venustum. Lusianthridin exhibits anti-migratory property at nontoxic concentrations. Lusianthridin enhances c-Myc degradation through the inhibition of Src-STAT3 signali...		Others , c-Myc
T72040	c-Myc inhibitor 7
	C-Myc Inhibitor 7, serving as both a c-Myc inhibitor and a multi-target protein degrader, effectively degrades proteins c-MYC, CK1α, GSPT1, and IKZF1/2/3 across various tumor cell types. It holds potential for research i...
T9061	EN4	EN4 MYC inhibitor	c-Myc
	EN4 (EN4 MYC inhibitor) MYC inhibitor is a covalent ligand that targets cysteine 171 (C171) of MYC. It is selective for c-MYC over N-MYC and L-MYC, and inhibits MYC transcriptional activity, downregulates MYC targets, an...		c-Myc
T3686	10074-G5		c-Myc , Autophagy
	10074-G5 is an inhibitor of c-Myc-Max dimerization.		c-Myc , Autophagy
T4252	ML327		c-Myc , Autophagy
	ML327 is a MYC blocker. ML327 can also de-repress E-cadherin transcription and reverse Epithelial-to-Mesenchymal Transition (EMT).		c-Myc , Autophagy
T15665	KJ Pyr 9		c-Myc , Autophagy
	KJ Pyr 9 is an MYC inhibitor (Kd: 6.5 nM in vitro assay).		c-Myc , Autophagy
T9628	10074-A4		c-Myc
	10074-A4 is a c-Myc binding compound that associates with c-Myc370–409 and behaves like a “ligand cloud” around a “protein cloud”, with distinct features from that of a non-binding ligand.		c-Myc
T21065	Artemisitene		Others
	Artemisitene is the oxidized form of Artemisinin and is an antimalarial agent. Artemisinin precursors are the important basic substances for biosynthesis of Artemisinin, including Artemisinin B, Artemisitene, Artemisini...		Others
T4367	Mycro 3	Mycro-3	c-Myc , Autophagy
	Mycro 3 is potent and selective for c-Myc in whole cell assays.		c-Myc , Autophagy
T12132	MYCi361	NUCC-0196361	c-Myc
	MYCi361 (NUCC-0196361) is an inhibitor of MYC (binding to MYC with Kd of 3.2 μM).		c-Myc
T9033	BTYNB	MDK6620,BTYNB IMP1 Inhibitor	Others , c-Myc , NF-κB
	BTYNB (MDK6620) is an inhibitor of the oncofetal mRNA-binding protein IMP1 (IC50 = 5 μM for IMP1 binding to c-Myc mRNA). MDK6620 downregulates β-TrCP1 mRNA and reduces activation of nuclear transcriptional factors-kappa ...		Others , c-Myc , NF-κB
T12134	MYCMI-6	NSC354961	Apoptosis , c-Myc
	MYCMI-6 (NSC-354961) is a potent and selective inhibitor of endogenous MYC:MAX protein interactions，reduces proliferation and induces massive apoptosis in tumor tissue from a MYC-driven xenograft tumor model without seve...		Apoptosis , c-Myc
T60019	VPC-70063	Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)-	Apoptosis , PARP , c-Myc
	VPC-70063 (Thiourea, N-[3,5-bis(trifluoromethyl)phenyl]-N'-(phenylmethyl)-) is an inhibitor of c-Myc-MAX. VPC-70063 exhibits Myc-Max transcriptional activity inhibition of 106% with an IC50 of 8.9 μM and Myc-Max/UBE2C do...		Apoptosis , PARP , c-Myc
T75239	c-Myc inhibitor 10
	C-Myc Inhibitor 10 (compound 17), exhibiting enhanced cellular potency, benefits from increased permeability due to the methylation of the morpholine nitrogen [1].
T79439	c-Myc inhibitor 12		c-Myc
	Compound 67h, also known as c-Myc inhibitor 12, is a potent inhibitor of c-Myc, exhibiting a pEC50 value of 6.4 [1].		c-Myc
T63359	c-Myc inhibitor 4
	c-Myc inhibitor 4 is a potent, orally active c-Myc-reducing compound. c-Myc is an important proto-oncogene, which is closely associated with the development of many tumors.
T72620	c-Myc inhibitor 9
	c-Myc Inhibitor 9 (Compound 332) is an effective c-Myc inhibitor, exhibiting a logEC50 of ≥6, and demonstrating significant tumor growth inhibition in nude mouse models. This compound is utilized in cancer research.
T79438	c-Myc inhibitor 11		c-Myc
	c-Myc inhibitor 11 (Compound 67e), a c-MYC inhibitor (p EC 50 : 6.4), exhibits high clearance, a moderate volume of distribution, and a short half-life in rat pharmacokinetic assays, making it suitable for cancer researc...		c-Myc
T10352	APTO-253	LOR-253,LT-253	Apoptosis , c-Myc , KLF
	APTO-253 (LOR-253) inhibits c-Myc expression, stabilizes G-quadruplex DNA, and induces cell cycle arrest and apoptosis in acute myeloid leukemia cells. APTO-253 mediates anticancer activity through the induction of the K...		Apoptosis , c-Myc , KLF